Genes encoding the NF-kB core signaling proteins.
| PAG Title | Genes encoding the NF-kB core signaling proteins. |
| PAG ID | MAX000922 |
| Type | A |
| Source Link |  MSigDB |
| Publication Reference | NA |
| PAG Description | This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-kappaB family of transcription factors. NF-kappaB signaling is primarily regulated by inhibitor kappaB (IkappaB) proteins and the IkappaB kinase complex through two major pathways: the canonical and non-canonical NF-kappaB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-kappaB. |
| Species | Homo sapiens |
| nCoCo Score | 3,987 |
| Base PAG ID | MAX000922 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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